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Demand has outstripped manufacturing capacity at various points, leading to periodic shortages

Some compounding pharmacies also offer sublingual (under-the-tongue) formulations, but these have not been extensively studied and the FDA has raised concerns about salt-form variations

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[61] In 1998, a team of researchers at Novo Nordisk led by Lotte Bjerre Knudsen developed liraglutide, a GLP-1 receptor agonist that could be used to treat diabetes

The other thing is that patients with diabetes may have autonomic dysfunction that's a known complication of diabetes, so they don't regulate blood pressure well

Studies have shown that after 68 weeks (12 to 15 months) of Wegovy treatment, average weight loss is to the tune of 15% of the starting body weight